DIN 58904:1998-04

The document is applicable to the determination of protein C activity in plasma and protein C concentrates using a chromogenic peptide substrate. The purpose is to achieve comparable results for the protein C content in a given sample. Essential preconditions for achieving this objective are a standardized procedure for calibration of the method as well as the use or reference materials with a defined protein C content. which has been determined by calibration against the International Standard of WHO for protein C valid at the time of use.